There has been some concern as of late with creatine being implicating in increasing the Testosterone:DHT ratio in healthy volunteers, mainly as DHT is more androgenic and encourages hair loss [x] (in those genetically susceptible to androgen-induced hair loss) due to being both more potent and staying at the androgen receptor longer. [x]
The purpose of this article is to elucidate these relations, the main articles under review are:
- Three Weeks of Creatine Monohydrate Supplementation affects Dihydrotestosterone to Testosterone Ratio in College-Aged Rugby Players (Main Article under Review)
- A response to the above article
An ultraviolet scan between the wavelengths of 200 and 360 nm revealed no interferences exceptfor creatinine.
Because of the potential clinical relevance of the endocrine results of this study and the high frequency of individuals using creatine supplementation without monitoring, further investigation is warranted.